The MMR vaccine: Take it or leave it?

Dear Dr. Donya,

Our 13-month-old son is due for his MMR (measles, mumps and rubella) shot within the next one or two months, but we've heard that there is a reported possible link to "autism" as a side effect of this vaccination.

Our pediatrician says this was "last year's biggest market rumor and nothing more!"

We nevertheless remain concerned and your views and advice would be much appreciated.

-- David

Dear David,

The MMR vaccine, which contains three vaccines in a single shot, has succeeded in virtually eliminating measles, mumps and rubella.

In the The Lancet in 1998, researchers described that 12 children developed behavioral problems, including autism, shortly after receiving the MMR vaccine. In eight of these children, the onset of their behavioral condition was linked, by parents or their physicians, with the vaccination. The authors note, however, that their study did not prove an association between MMR and the conditions described in these children.

Most cases of autism result from events in the prenatal period or shortly after birth. There is considerable concern with regard to the MMR vaccine because autistic symptoms typically do not become evident until the child's second year of life, which is about the same time that this vaccine is first administered.

Current scientific evidence does not support the hypothesis that the MMR vaccine, or any combination of vaccines, causes the development of autism or its regressive forms.

Epidemiologic studies have shown no relationship between MMR vaccinations in children and the development of autism.

My opinion is the effects of the disease far out ways the non- supported risk of taking the vaccine.

-- Dr. Donya