{
    "success": true,
    "data": {
        "id": 1947959,
        "msgid": "human-ageing-occurs-in-major-waves-at-these-two-ages-1788015025",
        "date": "2026-08-29 20:43:00",
        "title": "Human Ageing Occurs in Major Waves at These Two Ages",
        "author": "Wisnu Arto Subari",
        "source": "MEDIA_INDONESIA",
        "tags": "",
        "topic": "Health",
        "summary": "New research published in Nature Aging reveals that human ageing does not follow a steady, linear decline but instead accelerates in distinct waves at around ages 44 and 60. Scientists from Stanford School of Medicine tracked over 135,000 biological markers in 108 participants and found that roughly 81 percent of ageing-related molecules shift sharply at these two life stages. The findings suggest opportunities for more precisely timed preventive care and medical interventions.",
        "content": "<p>Ageing rarely follows a steady, straight line. While some people\nbegin to notice physical changes early on, others appear to maintain the\nsame energy and appearance for decades. For a long time, science\nregarded ageing as a slow and predictable process shaped by time,\ngenetics, and environment.<\/p>\n<p>However, recent research challenges that notion. Scientists now show\nthat the human body undergoes ageing in distinct waves, rather than\nthrough a constant decline. These changes affect how the body processes\neveryday substances, regulates metabolism, and responds to\ncardiovascular stress.<\/p>\n<p>The findings point to specific moments when the body quietly \u2018changes\ngear\u2019. Instead of fading gradually, biological systems appear to\nreorganise themselves, creating periods when physical decline becomes\nmore noticeable and harder to ignore.<\/p>\n<p>The study, published in the journal Nature Aging, monitored 108\nparticipants over several years. Researchers tracked more than 135,000\nbiological markers linked to health and ageing, creating one of the most\ndetailed views yet of how the body evolves over time.<\/p>\n<p>The results showed a clear pattern. Around 81 percent of the\nmolecules associated with ageing did not change steadily. Instead, they\nshifted sharply at two age points: around 44 years old and again near 60\nyears old. These moments mark significant changes in metabolism, immune\nresponse, and how the body handles substances such as alcohol and\ncaffeine.<\/p>\n<p>According to the research team from Stanford School of Medicine,\nthese shifts indicate that ageing accelerates during certain life\nstages. Understanding when these changes occur could help doctors and\nresearchers better predict health risks and design more precise\ntreatments.<\/p>\n<p>Although the study did not identify a single cause behind these\ntransitions, the researchers believe that lifestyle plays an important\nrole. Middle age often brings increased stress, changes in sleep\nquality, and higher alcohol consumption\u2014all factors known to affect\nheart health and immunity.<\/p>\n<p>Many people report sudden physical changes in their mid-forties,\nincluding weight gain, loss of muscle mass, and slower recovery. Similar\nshifts are also felt around age sixty, when strength and endurance\nappear to decline faster than expected.<\/p>\n<p>These experiences suggest that the body may become less tolerant\nduring those periods. Habits that once had a small, barely visible\nimpact can suddenly have a major effect, making health maintenance feel\nmore demanding and something that must be done deliberately.<\/p>\n<p>Understanding that ageing has major turning points offers a more\nhopeful perspective. Instead of viewing decline as inevitable, these\nfindings highlight opportunities for prevention and adjustment. Knowing\nwhen the body is more vulnerable allows individuals to act earlier and\nmore wisely.<\/p>\n<p>For medical research, the implications are significant. Drug\ndevelopment and preventive care can be timed to these biological windows\nto improve effectiveness and long-term outcomes. In this sense, ageing\nbecomes something that can be managed, rather than merely endured.<\/p>\n<p>Although growing older cannot be avoided, the way people experience\nit is not rigid. By recognising these critical stages, science opens the\ndoor to a more informed, balanced, and resilient approach to ageing.<\/p>",
        "url": "https:\/\/jawawa.id\/newsitem\/human-ageing-occurs-in-major-waves-at-these-two-ages-1788015025",
        "image": ""
    },
    "sponsor": "Okusi Associates",
    "sponsor_url": "https:\/\/okusiassociates.com"
}