{
    "success": true,
    "data": {
        "id": 1794854,
        "msgid": "air-pollution-exposure-during-pregnancy-can-disrupt-foetal-development-1781067517",
        "date": "2026-06-10 10:43:59",
        "title": "Air Pollution Exposure During Pregnancy Can Disrupt Foetal Development",
        "author": "Qommarria Rostanti",
        "source": "REPUBLIKA",
        "tags": "",
        "topic": "Health",
        "summary": "Exposure to air pollution during pregnancy poses a serious threat to foetal development, a paediatrician has warned. Pollutants such as PM2.5 can penetrate the placental barrier, triggering inflammation and oxidative stress that may impair organ growth and increase the risk of premature birth and low birth weight. The combination of pollution and rising temperatures from climate change is also linked to higher risks of preeclampsia.",
        "content": "<p>Climate change, which triggers heatwaves, is increasingly worsening\nair quality in various regions. This condition not only impacts public\nhealth in general, but also poses a serious threat to vulnerable groups,\nespecially pregnant women, foetuses, and newborns. Paediatric specialist\nand member of the Indonesian Paediatric Society\u2019s (IDAI) Environmental\nHealth and Climate Change Task Force, Dr Riyadi, stated that prenatal\nexposure to air pollution can disrupt foetal development in the womb.\nAccording to him, air pollutants such as fine particulate matter PM2.5\nand PM10 can penetrate the placental barrier. \u201cThis condition opens the\nway for harmful substances to enter the foetal environment and trigger\nvarious complex biological disorders during pregnancy,\u201d Dr Riyadi said\nduring a webinar held by the Indonesian Paediatric Society (IDAI) on\nTuesday. In terms of biological mechanisms, Dr Riyadi said the exposure\nalso causes oxidative stress and inflammation in the bodies of the\nmother and foetus. This condition is marked by an increase in\ninflammation-triggering compounds that can disrupt placental development\nand foetal growth. According to Dr Riyadi, disruption to the placenta\ncan further lead to impaired organogenesis, immune system function, and\nlung maturation processes in the foetus. In other words, pollution\nexposure not only affects physical growth but also the development of\nvital organ functions from the earliest phase of life. From a clinical\nperspective, various studies show the serious impact of this condition.\nPrenatal air pollution exposure is linked to an increased risk of\nprematurity, low birth weight, restricted foetal growth, and neonatal\ndeath. \u201cOther studies have also found that exposure to PM10 and ozone\nduring the first trimester of pregnancy is reported to reduce infant\nbirth weight. Meanwhile, exposure to sulphur dioxide in the second\ntrimester can increase TNF-a levels in the mother and lead to a\nreduction in foetal weight,\u201d said Dr Riyadi. Furthermore, other\npollutants such as heavy metals, black carbon, and nitrogen dioxide also\ncontribute to foetal metabolic disorders. Dr Riyadi also highlighted\nepigenetic changes, including microRNA disruption, which can affect a\nchild\u2019s long-term development. The impact does not stop during pregnancy\nbut also increases the risk of metabolic disorders and early infections.\nThe combination of increased PM2.5 and temperature due to climate change\nis said to increase foetal blood pressure and cortisol levels in\npregnant women. This condition is then linked to an increased risk of\npreeclampsia in the third trimester of pregnancy.<\/p>",
        "url": "https:\/\/jawawa.id\/newsitem\/air-pollution-exposure-during-pregnancy-can-disrupt-foetal-development-1781067517",
        "image": ""
    },
    "sponsor": "Okusi Associates",
    "sponsor_url": "https:\/\/okusiassociates.com"
}